Amelioration of Non-Alcoholic Steatohepatitis by Atractylodes macrocephala Polysaccharide, Chlorogenic Acid, and Geniposide Combination Is Associated With Reducing Endotoxin Gut Leakage

Amelioration of Non-Alcoholic Steatohepatitis by Atractylodes macrocephala Polysaccharide, Chlorogenic Acid, and Geniposide Combination Is Associated With Reducing Endotoxin Gut Leakage

Gut-derived lipopolysaccharide (LPS) leaking through the dysfunctional intestinal barrier contributes to the onset of non-alcoholic steatohepatitis (NASH) by triggering inflammation in the liver. In the present study, a combination consisting of Atractylodes macrocephala polysaccharide (A), chloroge...

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Bibliographic Details
Main Authors: Jing Leng, Hua-jie Tian, Yi Fang, Yi-yang Hu, Jing-hua Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Atractylodes macrocephala polysaccharide
chlorogenic acid
geniposide
non-alcoholic steatohepatitis
lipopolysaccharide
intestinal tight junctions
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.827516/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.827516/full

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