S-Ketamine oral thin film—Part 2: Population pharmacodynamics of S-ketamine, S-norketamine and S-hydroxynorketamine

S-Ketamine oral thin film—Part 2: Population pharmacodynamics of S-ketamine, S-norketamine and S-hydroxynorketamine

Ketamine is a versatile drug used for many indications and is administered via various routes. Here, we report on the pharmacodynamics of sublingual and buccal fast-dissolving oral-thin-films that contain 50 mg of S-ketamine in a population of healthy male and female volunteers. Twenty volunteers re...

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Bibliographic Details
Main Authors: Pieter Simons, Erik Olofsen, Monique van Velzen, Maarten van Lemmen, Tom van Dasselaar, Patrick Mohr, Florian Hammes, Rutger van der Schrier, Marieke Niesters, Albert Dahan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pain Research
Subjects:
ketamine
S-ketamine
pharmacodynamics
antinociception
modeling
oral transmucosal film
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2022.946487/full

Internet

https://www.frontiersin.org/articles/10.3389/fpain.2022.946487/full

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