Bamboo Shark as a Small Animal Model for Single Domain Antibody Production

Bamboo Shark as a Small Animal Model for Single Domain Antibody Production

The development of shark single domain antibodies (sdAbs) is hindered by the high cost and tediousness of large-sized shark farming. Here, we demonstrated white-spotted bamboo sharks (Chiloscyllium plagiosum) being cultivated commercially as a promising small animal model to produce sdAbs. We found...

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Bibliographic Details
Main Authors: Likun Wei, Meiniang Wang, Haitao Xiang, Yuan Jiang, Jinhua Gong, Dan Su, M. A. R. Al Azad, Hongming Dong, Limin Feng, Jiajun Wu, Leo Lai Chan, Naibo Yang, Jiahai Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
single domain antibody
bamboo shark
IgNAR
immunization
vNAR
immune repertoire
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.792111/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2021.792111/full

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