Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma

Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma

<p>Abstract</p> <p>Background</p> <p>Cyclooxygenase-2 (COX-2, <it>PTGS2</it>) plays an important role in colorectal carcinogenesis. COX-2 overexpression in colorectal cancer is inversely associated with microsatellite instability (MSI) and the CpG island met...

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Detalles Bibliográficos
Autores principales: Kirkner Gregory J, Chan Andrew T, Glickman Jonathan N, Suemoto Yuko, Ohnishi Mutsuko, Nosho Katsuhiko, Kawasaki Takako, Mino-Kenudson Mari, Fuchs Charles S, Ogino Shuji
Formato: Artículo
Lenguaje:English
Publicado: BMC 2008-01-01
Colección:BMC Cancer
Acceso en línea:http://www.biomedcentral.com/1471-2407/8/33

Internet

http://www.biomedcentral.com/1471-2407/8/33

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