TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study

<p>Abstract</p> <p>Background</p> <p>Histological phenotype and clinical behaviour of malignant tumours are not only dependent on alterations in the epithelial cell compartment, but are affected by their interaction with inflammatory cells and tumour-associated stroma....

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Bibliographic Details
Main Authors: Papadopoulos Thomas, Croner Roland, Merkel Susanne, Bacman David, Brueckl Wolfgang, Dimmler Arno
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/156