Proteomics validate circulating GDF-15 as an independent biomarker for COVID-19 severity

IntroductionGrowth differentiation factor 15 (GDF-15) was originally described as a stress-induced cytokine, and a biomarker of aging and cardiovascular diseases. We hypothesized that circulating GDF-15 would be associated with COVID-19 disease severity. Herein, we explored this hypothesis in a larg...

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Bibliographic Details
Main Authors: Simeng Bu, Léna Royston, Tsoarello Mabanga, Carolina A. Berini, Cécile Tremblay, Bertrand Lebouché, Joseph Cox, Cecilia T. Costiniuk, Madeleine Durand, Stephane Isnard, Jean-Pierre Routy
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1377126/full