Calreticulin is important for the development of renal fibrosis and dysfunction in diabetic nephropathy

Calreticulin is important for the development of renal fibrosis and dysfunction in diabetic nephropathy

Previously, our lab showed that the endoplasmic reticulum (ER) and calcium regulatory protein, calreticulin (CRT), is important for collagen transcription, secretion, and assembly into the extracellular matrix (ECM) and that ER CRT is critical for TGF-β stimulation of type I collagen transcription t...

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Bibliographic Details
Main Authors: Ailing Lu, Manuel A. Pallero, Benjamin Y. Owusu, Anton V. Borovjagin, Weiqi Lei, Paul W. Sanders, Joanne E. Murphy-Ullrich
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Matrix Biology Plus
Subjects:
Diabetic nephropathy
Collagen
NFAT
Calreticulin
Fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028520300156

Internet

http://www.sciencedirect.com/science/article/pii/S2590028520300156

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