Cingulate Alpha-2A Adrenoceptors Mediate the Effects of Clonidine on Spontaneous Pain Induced by Peripheral Nerve Injury

The anterior cingulate cortex (ACC) is an important brain area for the regulation of neuropathic pain. The α2A adrenoceptor is a good target for pain management. However, the role of cingulate α2A adrenoceptors in the regulation of neuropathic pain has been less studied. In this study, we investigat...

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Bibliographic Details
Main Authors: Yong-Jie Wang, Zhen-Xing Zuo, Cheng Wu, Li Liu, Zhi-Hui Feng, Xiang-Yao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00289/full