Single-Cell RNA Transcriptomics Reveals the State of Hepatic Lymphatic Endothelial Cells in Hepatitis B Virus-Related Acute-on-Chronic Liver Failure

Single-Cell RNA Transcriptomics Reveals the State of Hepatic Lymphatic Endothelial Cells in Hepatitis B Virus-Related Acute-on-Chronic Liver Failure

Acute-on-chronic liver failure (ACLF) is an acutely decompensated cirrhosis syndrome with high short-term mortality. Very little is known about the relationship between the lymphatic system and ACLF. We explored the role of hepatic lymphatic vessels (LVs) and lymphatic endothelial cells (LyECs) in A...

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Bibliographic Details
Main Authors: Pengpeng Zhang, Hao Li, Chen Zhou, Kai Liu, Bo Peng, Xingguo She, Ke Cheng, Hong Liu, Yingzi Ming
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
cirrhosis
acute-on-chronic liver failure
lymphangiogenesis
lymphatic endothelial cells
ScRNA-seq
secreted phosphoprotein 1
Online Access:https://www.mdpi.com/2077-0383/11/10/2910

Internet

https://www.mdpi.com/2077-0383/11/10/2910

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