Minor temperature shifts do not affect chromosomal ploidy but cause transcriptomic changes in Leishmania braziliensis promastigotes in vitro

Minor temperature shifts do not affect chromosomal ploidy but cause transcriptomic changes in Leishmania braziliensis promastigotes in vitro

BACKGROUND The leishmaniases are complex neglected diseases caused by protozoan parasites of the genus Leishmania. Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis in the New World. In recent studies, genomic changes such as chromosome and gene copy number variations...

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Bibliographic Details
Main Authors: Nathalia Ballesteros, Nubia M Vásquez, Luz H Patiño, Lissa Cruz-Saavedra, Juan David Ramírez
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2020-04-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Leishmania braziliensis
temperature shift
copy number variation
transcriptome profile
heat shock protein
amastin-like protein
ABC transporter
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100312&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100312&tlng=en

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