A Quasi-Physiological Microfluidic Blood-Brain Barrier Model for Brain Permeability Studies

A Quasi-Physiological Microfluidic Blood-Brain Barrier Model for Brain Permeability Studies

Microfluidics-based organ-on-a-chip technology allows for developing a new class of in-vitro blood-brain barrier (BBB) models that recapitulate many hemodynamic and architectural features of the brain microvasculature not attainable with conventional two-dimensional platforms. Herein, we describe an...

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Bibliographic Details
Main Authors: Behnam Noorani, Aditya Bhalerao, Snehal Raut, Ehsan Nozohouri, Ulrich Bickel, Luca Cucullo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
endothelium
alternative
drug discovery
pericytes
stem cells
co-culture
Online Access:https://www.mdpi.com/1999-4923/13/9/1474

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https://www.mdpi.com/1999-4923/13/9/1474

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