Pitfalls in the Application of Dispase-Based Keratinocyte Dissociation Assay for In Vitro Analysis of Pemphigus Vulgaris

Pitfalls in the Application of Dispase-Based Keratinocyte Dissociation Assay for In Vitro Analysis of Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a chronic, life-altering autoimmune disease due to the production of anti-desmoglein antibodies causing the loss of cell–cell adhesion in keratinocytes (acantholysis) and blister formation in both skin and mucous membranes. The dispase-based keratinocyte dissociation assay...

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Bibliographic Details
Main Authors: Morna F. Schmidt, Maria Feoktistova, Diana Panayotova-Dimitrova, Ramona A. Eichkorn, Amir S. Yazdi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Vaccines
Subjects:
keratinocytes
desmosomes
autoimmune bullous diseases
pemphigus
in vitro analysis
Online Access:https://www.mdpi.com/2076-393X/10/2/208

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https://www.mdpi.com/2076-393X/10/2/208

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