Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation

Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation

IntroductionBTBD8 has been identified as a susceptible gene for inflammatory bowel diseases (IBD). However, the function of BTBD8 in normal development and IBD pathogenesis remains unknown.MethodsWe administered drinking water with 3% dextran sodium sulfate (DSS) to wild-type (WT) and Btbd8 knockout...

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Bibliographic Details
Main Authors: Xiaoqiong Yang, Zichan He, Qiman Dong, Shanshan Nai, Xiaowei Duan, Jiayu Yu, Nannan Zhao, Xiaoling Du, Lingyi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
BTBD8
intestinal barrier integrity
DSS
inflammation
inflammatory bowel disease (IBD)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382661/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382661/full

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