Basic mechanisms of platelet receptor shedding
Proteolytic shedding of the extracellular ectodomain of platelet receptors provides a key mechanism for irreversible loss of ligand-binding capacity, and for regulating platelet function in health and disease. Platelets derived from megakaryocytes are small anucleate cells in peripheral blood, with...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-05-01
|
Series: | Platelets |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/09537104.2016.1235690 |