Molecular and metabolic alterations of 2,3-dihydroquinazolin-4(1H)-one derivatives in prostate cancer cell lines

Abstract Prostate cancer (PC) is the second most common tumor in males worldwide. The lack of effective medication and the development of multidrug resistance towards current chemotherapeutic agents urge the need to discover novel compounds and therapeutic targets for PC. Herein, seven synthesized 2...

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Bibliographic Details
Main Authors: Lina A. Dahabiyeh, Wafa Hourani, Wesam Darwish, Farah Hudaib, Bashaer Abu-Irmaileh, Pran Kishore Deb, Katharigatta N. Venugopala, Viresh Mohanlall, Rana Abu-Dahab, Mohammad H. Semreen, Yasser Bustanji
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26148-4