Fingolimod (FTY720) Preserves High Energy Phosphates and Improves Cardiac Function in Heterotopic Heart Transplantation Model
During heart transplantation, donor heart leads to reduced oxygen supply resulting in low level of high energy phosphate (HEP) reserves in cardiomyocyte. Lower HEP is one of the underlying reasons of cell death due to ischemia. In this study we investigated the role of Fingolimod (FTY720) in heart t...
Main Authors: | Naseer Ahmed, Javeria Farooq, Soban Sadiq, Sultan Ayoub Meo, Azam Jan, Faisal H. Cheema, Giuseppe Faggian, Alessio Rungatscher |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/18/6548 |
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