The IFN-stimulated gene IFI27 counteracts innate immune responses after viral infections by interfering with RIG-I signaling

The IFN-stimulated gene IFI27 counteracts innate immune responses after viral infections by interfering with RIG-I signaling

The recognition of viral nucleic acids by host pattern recognition receptors (PRRs) is critical for initiating innate immune responses against viral infections. These innate immune responses are mediated by the induction of interferons (IFNs), IFN-stimulated genes (ISGs) and pro-inflammatory cytokin...

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Bibliographic Details
Main Authors: Laura Villamayor, Darío López-García, Vanessa Rivero, Luis Martínez-Sobrido, Aitor Nogales, Marta L. DeDiego
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Microbiology
Subjects:
IFI27
innate immune responses
interferon
inflammation
influenza
SARS-CoV-2
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1176177/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1176177/full

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