Impaired frequencies and function of platelets and tissue remodeling in chronic Chagas disease.

Chronic inflammation, as a consequence of the persistent infection with Trypanosoma cruzi, leads to continuous activation of the immune system in patients with chronic Chagas disease. We have previously shown that increased sera levels of soluble P-selectin are associated with the severity of the ca...

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Bibliographic Details
Main Authors: Claudia Pengue, Gonzalo Cesar, María Gabriela Alvarez, Graciela Bertocchi, Bruno Lococo, Rodolfo Viotti, María Ailén Natale, Melisa D Castro Eiro, Silvia S Cambiazzo, Nancy Perroni, Myriam Nuñez, María Cecilia Albareda, Susana A Laucella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218260