Uropathogenic Escherichia coli Infection Compromises the Blood-Testis Barrier by Disturbing mTORC1-mTORC2 Balance

Uropathogenic Escherichia coli Infection Compromises the Blood-Testis Barrier by Disturbing mTORC1-mTORC2 Balance

The structural and functional destruction of the blood-testis barrier (BTB) following uropathogenic E. coli (UPEC) infection may be a critical component of the pathologic progress of orchitis. Recent findings indicate that the mammalian target of the rapamycin (mTOR)-signaling pathway is implicated...

Full description

Bibliographic Details
Main Authors: Yongning Lu, Miao Liu, Nicholas J. Tursi, Bin Yan, Xiang Cao, Qi Che, Nianqin Yang, Xi Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
blood-testis barrier
uropathogenic E. coli
orchitis
mammalian target of rapamycin
male infertility
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.582858/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.582858/full

Similar Items