YKL-40 changes are not detected in post-mortem brain of patients with Alzheimer’s disease and frontotemporal lobar degeneration

YKL-40 changes are not detected in post-mortem brain of patients with Alzheimer’s disease and frontotemporal lobar degeneration

Abstract Background YKL-40 (Chitinase 3-like I) is increased in CSF of Alzheimer’s disease (AD) and frontotemporal lobar degeneration (FTLD) patients and is therefore considered a potential neuroinflammatory biomarker. Whether changed YKL-40 levels in the CSF reflect dysregulation of YKL-40 in the b...

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Bibliographic Details
Main Authors: Yanaika S. Hok-A-Hin, Jeroen J. M. Hoozemans, William T. Hu, Dorine Wouters, Jennifer C. Howell, Alberto Rábano, Wiesje M. van der Flier, Yolande A. L. Pijnenburg, Charlotte E. Teunissen, Marta del Campo
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
YKL-40
Chitinase 3-like I
Alzheimer’s disease
Frontotemporal lobar degeneration
Neuroinflammation
Brain
Online Access:https://doi.org/10.1186/s13195-022-01039-y

Internet

https://doi.org/10.1186/s13195-022-01039-y

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