Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain

Abstract Focused ultrasound and microbubbles can non-invasively and locally deliver therapeutics and imaging agents across the blood–brain barrier. Uniform treatment and minimal adverse bioeffects are critical to achieve reliable doses and enable safe routine use of this technique. Towards these aim...

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Bibliographic Details
Main Authors: William Lim Kee Chang, Tiffany G. Chan, Federica Raguseo, Aishwarya Mishra, Dani Chattenton, Rafael T. M. de Rosales, Nicholas J. Long, Sophie V. Morse
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33671-5