Human Complement Receptor Type 1/CD35 Is an Epstein-Barr Virus Receptor

Epstein-Barr virus (EBV) attachment to primary B cells initiates virus entry. Although CD21 is the only known receptor for EBVgp350/220, a recent report documents EBV-infected B cells from a patient genetically deficient in CD21. On normal resting B cells, CD21 forms two membrane complexes: one with...

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Bibliographic Details
Main Authors: Javier G. Ogembo, Lakshmi Kannan, Ionita Ghiran, Anne Nicholson-Weller, Robert W. Finberg, George C. Tsokos, Joyce D. Fingeroth
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000302