Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools

The identification of breast cancer cell subpopulations featuring truly malignant stem cell qualities is a challenge due to the complexity of the disease and lack of general markers. By combining extensive single-cell gene expression profiling with three functional strategies for cancer stem cell en...

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Bibliographic Details
Main Authors: Nina Akrap, Daniel Andersson, Eva Bom, Pernilla Gregersson, Anders Ståhlberg, Göran Landberg
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003719