Insulin resistance and steatosis in chronic hepatitis C

In chronic hepatitis C, insulin resistance (IR) and type 2 diabetes mellitus (DM) are more prevalent than in healthy controls or in chronic hepatitis B patients. HCV infection promotes IR mainly through increased TNF-α and cytokine suppressor (SOCS-3) production. Both events inhibit insulin receptor...

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Bibliographic Details
Main Authors: Mariana V. Machado, Helena Cortez-Pinto
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119318290