Effects of Systemic or Local Administration of Mesenchymal Stem Cells from Patients with Osteoporosis or Osteoarthritis on Femoral Fracture Healing in a Mouse Model

Effects of Systemic or Local Administration of Mesenchymal Stem Cells from Patients with Osteoporosis or Osteoarthritis on Femoral Fracture Healing in a Mouse Model

The purpose of this study was to analyze the regenerative capacity of mesenchymal stem cells (MSCs) in the treatment of fractures. MSCs extracted from patients with osteoporotic hip fractures or hip osteoarthritis undergoing hip replacement surgeries were cultured and injected into mice with femoral...

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Bibliographic Details
Main Authors: Esther Laguna, María Isabel Pérez-Núñez, Álvaro del Real, Guillermo Menéndez, José A. Sáinz-Aja, Laura López-Delgado, Carolina Sañudo, Alicia Martín, Remigio Mazorra, Diego Ferreño, Belén García-Montesinos, José A. Riancho
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
mesenchymal stem cells
bone regeneration
animal model
micro-CT
histological study
Online Access:https://www.mdpi.com/2218-273X/12/5/722

Internet

https://www.mdpi.com/2218-273X/12/5/722

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