Coamorphous Atorvastatin Calcium to Improve its Physicochemical and Pharmacokinetic Properties

Purpose: Atorvastatin calcium (ATC) is classified as class II (low solubility and high permeability) compound according to the biopharmaceutical classification system. The amorphous form of ATC possesses higher solubility, dissolution rate, and bioavailability than its crystalline form. Coamorphous...

Full description

Bibliographic Details
Main Authors: Ali Shayanfar, Hamed Ghavimi, Hamed Hamishekar, Abolghasem Jouyban
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/19174