Effects of anastrozole on Ki-67 antigen expression in the vaginal epithelium of female rats in persistent estrus

Effects of anastrozole on Ki-67 antigen expression in the vaginal epithelium of female rats in persistent estrus

OBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. MET...

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Bibliographic Details
Main Authors: Diego Cipriano Chagas, Maria da Conceição Barros-Oliveira, Pedro Vitor Lopes-Costa, Renato de Oliveira Pereira, Mariella de Almeida Melo, Danylo Rafhael Costa-Silva, Carine Soares Borges, Jackeline Lopes Viana, Alesse Ribeiro dos Santos, Gil Facina, Benedito Borges da Silva
Format: Article
Language:English
Published: Elsevier España 2020-04-01
Series:Clinics
Subjects:
Anastrozole
Rat
Vagina
Proliferation
Ki-67
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100224&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100224&tlng=en

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