PPARγ antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function
Acquired aplastic anemia is an immune-mediated disease, in which T cells target hematopoietic cells; at presentation, the bone marrow is replaced by fat. It was reported that bone marrow adipocytes were negative regulators of hematopoietic microenvironment. To examine the role of adipocytes in bone...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2016-01-01
|
| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/7607 |