Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?

The PTEN gene encodes for the phosphatase and tensin homolog; it is a tumor suppressor gene that is among the most frequently inactivated genes throughout the human cancer spectrum. The most recent sequencing approaches have allowed the identification of PTEN genomic alterations, including deletion,...

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Bibliographic Details
Main Authors: Raghavendra Tejo Karthik Poluri, Étienne Audet-Walsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00246/full