Insulin Signaling in the Aging of Healthy and Proteotoxically Stressed Mechanosensory Neurons

Insulin Signaling in the Aging of Healthy and Proteotoxically Stressed Mechanosensory Neurons

Insulin signaling is central to cellular metabolism and organismal aging. However, the role of insulin signaling in natural and proteotoxically stressed aging neurons has yet to be fully described. We studied aging of Caenorbaditis elegans mechanosensory neurons expressing a neurotoxic expanded poly...

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Bibliographic Details
Main Authors: Courtney eScerbak, Elena M Vayndorf, Alex eParker, Christian eNeri, Monica eDriscoll, Barbara Elan Taylor
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
neuronal aging
insulin signaling2
neurodegeneration3
Huntington’s Disease4
Caenorhabditis elegans5
proteotoxicity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00212/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00212/full

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