Application of sample size re-estimation in clinical trials: A systematic review

Background: Sample size re-estimation (SSR) is a method used to recalculate sample size during clinical trial conduct to address a lack of adequate information and can have a significant impact on study size, duration, resources, and cost. Few studies to date have summarized the conditions and circu...

Full description

Bibliographic Details
Main Authors: Hirotaka Mano, Yuji Tanaka, Shunichiro Orihara, Junji Moriya
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Contemporary Clinical Trials Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865423001564