Clinical outcomes associated with antidepressant use in inflammatory bowel disease patients and a matched control cohort

Abstract Antidepressant medications (AMs) are frequently used in inflammatory bowel disease (IBD). Many AMs enhance serotonin (5-HT) availability, but this phenomenon may actually worsen IBD. We hypothesized that use of 5-HT-enhancing AMs would be associated with poor clinical outcomes in these diso...

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Bibliographic Details
Main Authors: Djibril M. Ba, Sanjay Yadav, Guodong Liu, Douglas L. Leslie, Kent E. Vrana, Matthew D. Coates
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51282-6