Comprehensive Analysis of Cytomegalovirus pp65 Antigen-Specific CD8+ T Cell Responses According to Human Leukocyte Antigen Class I Allotypes and Intraindividual Dominance

Comprehensive Analysis of Cytomegalovirus pp65 Antigen-Specific CD8+ T Cell Responses According to Human Leukocyte Antigen Class I Allotypes and Intraindividual Dominance

To define whether individual human leukocyte antigen (HLA) class I allotypes are used preferentially in human cytomegalovirus (CMV)-specific cytotoxic T lymphocyte responses, CD8+ T cell responses restricted by up to six HLA class I allotypes in an individual were measured in parallel using K562-bas...

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Bibliographic Details
Main Authors: Seung-Joo Hyun, Hyun-Jung Sohn, Hyun-Joo Lee, Seon-Duk Lee, Sueon Kim, Dae-Hee Sohn, Cheol-Hwa Hong, Haeyoun Choi, Hyun-Il Cho, Tai-Gyu Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
human leukocyte antigen class I
cytomegalovirus pp65
CD8+ T cell
immunodominant pattern
human leukocyte antigen restriction
preferential usage
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01591/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01591/full

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