Modulation of transcription burst amplitude underpins dosage compensation in the Drosophila embryo

Summary: Dosage compensation, the balancing of X-linked gene expression between sexes and to the autosomes, is critical to an organism’s fitness and survival. In Drosophila, dosage compensation involves hypertranscription of the male X chromosome. Here, we use quantitative live imaging and modeling...

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Bibliographic Details
Main Authors: Lauren Forbes Beadle, Hongpeng Zhou, Magnus Rattray, Hilary L. Ashe
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003935