Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells
To overcome genotoxicity, cells have evolved powerful and effective mechanisms to detect and respond to DNA lesions. RecQ Like Helicase‐4 (RECQL4) plays a vital role in DNA damage responses. RECQL4 is recruited to DNA double‐strand break (DSB) sites in a poly(ADP‐ribosyl)ation (PARylation)‐dependent...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-01-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.13917 |