Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells

To overcome genotoxicity, cells have evolved powerful and effective mechanisms to detect and respond to DNA lesions. RecQ Like Helicase‐4 (RECQL4) plays a vital role in DNA damage responses. RECQL4 is recruited to DNA double‐strand break (DSB) sites in a poly(ADP‐ribosyl)ation (PARylation)‐dependent...

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Bibliographic Details
Main Authors: Sunyoung Shin, Dongmin Kim, Hyemi Kim, Won‐Ho Cho, Gyungmin Kim, Joon‐Kyu Lee
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13917