Structure of putative tumor suppressor ALDH1L1

Tsybovsky et. al. report cryo-EM structures of tetrameric rat ALDH1L1 elucidating its architecture and domain interactions important for its functions. These findings emphasize the versatility of acyl/peptidyl carrier proteins in complex, highly dynamic enzymatic systems.

Bibliographic Details
Main Authors: Yaroslav Tsybovsky, Valentin Sereda, Marcin Golczak, Natalia I. Krupenko, Sergey A. Krupenko
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02963-9