Structure of putative tumor suppressor ALDH1L1
Tsybovsky et. al. report cryo-EM structures of tetrameric rat ALDH1L1 elucidating its architecture and domain interactions important for its functions. These findings emphasize the versatility of acyl/peptidyl carrier proteins in complex, highly dynamic enzymatic systems.
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02963-9 |