Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington’s disease

Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington’s disease

Abstract Obesity represents a global health problem and is characterized by metabolic dysfunctions and a low-grade chronic inflammatory state, which can increase the risk of comorbidities, such as atherosclerosis, diabetes and insulin resistance. Here we tested the hypothesis that the genetic deleti...

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Bibliographic Details
Main Authors: Rebeca P. M. Santos, Roberta Ribeiro, Talita H. Ferreira-Vieira, Rosaria D. Aires, Jessica M. de Souza, Bruna S. Oliveira, Anna Luiza D. Lima, Antônio Carlos P. de Oliveira, Helton J. Reis, Aline S. de Miranda, Erica M. L. Vieira, Fabiola M. Ribeiro, Luciene B. Vieira
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08924-4

Internet

https://doi.org/10.1038/s41598-022-08924-4

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