Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism

Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism

Motile kinesins are motor proteins that translocate along microtubules as they hydrolyze ATP. They share a conserved motor domain which harbors both ATPase and microtubule‐binding activities. An ATP hydrolysis mechanism involving two water molecules has been proposed based on the structure of the ki...

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Bibliographic Details
Main Authors: Paloma F. Varela, Mélanie Chenon, Christophe Velours, Kristen J. Verhey, Julie Ménétrey, Benoît Gigant
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:FEBS Open Bio
Subjects:
ATP hydrolysis mechanism
kinesin
microtubule
motor protein
X‐ray crystallography
Online Access:https://doi.org/10.1002/2211-5463.13101

Internet

https://doi.org/10.1002/2211-5463.13101

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