Mitochondrial DNA alterations of peripheral lymphocytes in acute lymphoblastic leukemia patients undergoing total body irradiation therapy

<p>Abstract</p> <p>Background</p> <p>Mitochondrial DNA (mtDNA) alterations, including mtDNA copy number and mtDNA 4977 bp common deletion (CD), are key indicators of irradiation-induced damage. The relationship between total body irradiation (TBI) treatment and mtDNA al...

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Bibliographic Details
Main Authors: Ji Fuyun, Hu Yide, Wen Quan, Qian Guisheng
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Radiation Oncology
Subjects:
Online Access:http://www.ro-journal.com/content/6/1/133