Increasing temperature denatures canine IgG reducing its ability to inhibit heartworm antigen detection

Increasing temperature denatures canine IgG reducing its ability to inhibit heartworm antigen detection

Abstract Background Immune complexing of target antigen to high affinity host antibody is recognized to impact the sensitivity of commercial heartworm antigen tests. Published information describing the effect of heat on interfering canine host antibodies is lacking. Immune complex dissociation (ICD...

Full description

Bibliographic Details
Main Authors: Jeff M. Gruntmeir, Jeff R. Abbott, Peter E. Kima, Maureen T. Long, Byron L. Blagburn, Heather S. Walden
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Parasites & Vectors
Subjects:
Immune complex dissociation
Heat treatment
Antigen
Antibody
Dirofilaria immitis
Canine heartworm
Online Access:https://doi.org/10.1186/s13071-023-05739-8

Internet

https://doi.org/10.1186/s13071-023-05739-8

Similar Items