Vitamin D Enhances Anticancer Properties of Cediranib, a VEGFR Inhibitor, by Modulation of VEGFR2 Expression in Melanoma Cells

Vitamin D Enhances Anticancer Properties of Cediranib, a VEGFR Inhibitor, by Modulation of VEGFR2 Expression in Melanoma Cells

Regardless of the recent groundbreaking introduction of personalized therapy, melanoma continues to be one of the most lethal skin malignancies. Still, a substantial proportion of patients either fail to respond to the therapy or will relapse over time, representing a challenging clinical problem. R...

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Bibliographic Details
Main Authors: Anna Piotrowska, Fernando Pereira Beserra, Justyna Marta Wierzbicka, Joanna Irena Nowak, Michał Aleksander Żmijewski
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
melanoma
vitamin D
calcipotriol
cediranib
anti-angiogenic therapy
VEGFR
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.763895/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.763895/full

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