Exact Primary Tumor Location in mCRC: Prognostic Value and Predictive Impact on Anti-EGFR mAb Efficacy

Exact Primary Tumor Location in mCRC: Prognostic Value and Predictive Impact on Anti-EGFR mAb Efficacy

Primary tumor sidedness (left vs. right) has prognostic and predictive impact on anti-EGFR agent efficacy and thus management of metastatic colorectal cancer (mCRC). This analysis evaluates the relevance of primary tumor location (PTL) in <i>RAS/BRAF</i> wild-type mCRC patients, when div...

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Bibliographic Details
Main Authors: Annabel H. S. Alig, Volker Heinemann, Michael Geissler, Ludwig Fischer von Weikersthal, Thomas Decker, Kathrin Heinrich, Swantje Held, Lena Weiss, Laura E. Fischer, Nicolas Moosmann, Arndt Stahler, Ivan Jelas, Annika Kurreck, Jobst C. von Einem, Anke C. Reinacher-Schick, Andrea Tannapfel, Clemens Giessen-Jung, Sebastian Stintzing, Dominik P. Modest
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
anti-EGFR antibody
metastatic colorectal cancer
primary tumor location
<i>RAS/BRAF</i> wild-type
Online Access:https://www.mdpi.com/2072-6694/14/3/526

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https://www.mdpi.com/2072-6694/14/3/526

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