Defining the molecular pathologies in cloaca malformation: similarities between mouse and human

Defining the molecular pathologies in cloaca malformation: similarities between mouse and human

Anorectal malformations are congenital anomalies that form a spectrum of disorders, from the most benign type with excellent functional prognosis, to very complex, such as cloaca malformation in females in which the rectum, vagina and urethra fail to develop separately and instead drain via a single...

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Bibliographic Details
Main Authors: Laura A. Runck, Anna Method, Andrea Bischoff, Marc Levitt, Alberto Peña, Margaret H. Collins, Anita Gupta, Shiva Shanmukhappa, James M. Wells, Géraldine Guasch
Format: Article
Language:English
Published: The Company of Biologists 2014-04-01
Series:Disease Models & Mechanisms
Subjects:
Anorectal malformation
Cloaca
Patterning
Epithelial differentiation
Sonic hedgehog
Online Access:http://dmm.biologists.org/content/7/4/483

Internet

http://dmm.biologists.org/content/7/4/483

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