Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

Abstract The yeast Saccharomyces cerevisiae is widely used as a cell factory to produce recombinant proteins. However, S. cerevisiae naturally secretes only a few proteins, such as invertase and the mating alpha factor, and its secretory capacity is limited. It has been reported that engineering pro...

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Bibliographic Details
Main Authors: Jichen Bao, Mingtao Huang, Dina Petranovic, Jens Nielsen
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:AMB Express
Subjects:
Retrograde trafficking
COPI vesicle
Protein secretion
GLO3
Saccharomyces cerevisiae
Online Access:http://link.springer.com/article/10.1186/s13568-018-0571-x

Internet

http://link.springer.com/article/10.1186/s13568-018-0571-x

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