African swine fever virus MGF360-11L negatively regulates cGAS-STING-mediated inhibition of type I interferon production

African swine fever virus MGF360-11L negatively regulates cGAS-STING-mediated inhibition of type I interferon production

Abstract The type I interferon (IFN-I) signaling pathway is an important part of the innate immune response and plays a vital role in controlling and eliminating pathogens. African swine fever virus (ASFV) encodes various proteins to evade the host’s natural immunity. However, the molecular mechanis...

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Bibliographic Details
Main Authors: Kaidian Yang, Ying Xue, Hui Niu, Chunwei Shi, Mingyang Cheng, Jianzhong Wang, Boshi Zou, Junhong Wang, Tianming Niu, Meiying Bao, Wentao Yang, Dandan Zhao, Yanlong Jiang, Guilian Yang, Yan Zeng, Xin Cao, Chunfeng Wang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Veterinary Research
Subjects:
MGF360-11L
IFN-I
signaling pathway
African swine fever virus
Online Access:https://doi.org/10.1186/s13567-022-01025-0

Internet

https://doi.org/10.1186/s13567-022-01025-0

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