Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score

Background Patients with cancer are particularly susceptible to SARS-CoV-2 infection. The systemic inflammatory response is a pathogenic mechanism shared by cancer progression and COVID-19. We investigated systemic inflammation as a driver of severity and mortality from COVID-19, evaluating the prog...

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Main Authors: Joan Brunet, Josep Tabernero, Mieke Van Hemelrijck, Salvatore Grisanti, Bruno Vincenzi, Isabel Ruiz-Camps, Juan Aguilar-Company, Daniela Ferrante, Oriol Mirallas, Amanda Jackson, Beth Russell, Ramon Salazar, Aleix Prat, Daniele Generali, Nadia Harbeck, Alberto Zambelli, Carlo Alberto Tondini, David J Pinato, Lorenza Rimassa, Armando Santoro, Neha Chopra, Tom Newsom-Davis, Gino M Dettorre, Saoirse Dolly, Angela Loizidou, John Chester, Uma Mukherjee, Mark Bower, Christopher C T Sng, Alexia Bertuzzi, Ricard Mesia, Ailsa Sita-Lumsden, Elia Seguí, Federica Biello, Pavetha Seeva, Gianpiero Rizzo, Michela Libertini, Antonio Maconi, Charlotte Moss, Rossella Bertulli, Diego Ottaviani, Raquel Liñan, Andrea Marrari, M Carmen Carmona-García, Valeria Tovazzi, Vittoria Fotia, Claudia Andrea Cruz, Nadia Saoudi-Gonzalez, Eudald Felip, Ariadna Roqué, Alvin J X Lee, David García-Illescas, Roxana Reyes, Yien Ning Sophia Wong, Lorenza Scotti, Javier Marco-Hernández, Andrea Patriarca, Lorenzo Chiudinelli, Michela Franchi, Alessandra Gennari, Nikolaos Diamantis
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/3/e002277.full