CapsNet-MHC predicts peptide-MHC class I binding based on capsule neural networks
Abstract The Major Histocompatibility Complex (MHC) binds to the derived peptides from pathogens to present them to killer T cells on the cell surface. Developing computational methods for accurate, fast, and explainable peptide-MHC binding prediction can facilitate immunotherapies and vaccine devel...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-04867-2 |