CapsNet-MHC predicts peptide-MHC class I binding based on capsule neural networks

Abstract The Major Histocompatibility Complex (MHC) binds to the derived peptides from pathogens to present them to killer T cells on the cell surface. Developing computational methods for accurate, fast, and explainable peptide-MHC binding prediction can facilitate immunotherapies and vaccine devel...

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Bibliographic Details
Main Authors: Mahmood Kalemati, Saeid Darvishi, Somayyeh Koohi
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04867-2