Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

Rare variation in protein coding sequence is poorly captured by GWAS arrays and has been hypothesized to contribute to disease heritability. Using the Illumina HumanExome SNP array, we successfully genotyped 191,032 common and rare non-synonymous, splice site, or nonsense variants in a multiethnic s...

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Bibliografski detalji
Glavni autori: Christopher A Haiman, Ying Han, Ye Feng, Lucy Xia, Chris Hsu, Xin Sheng, Loreall C Pooler, Yesha Patel, Laurence N Kolonel, Erin Carter, Karen Park, Loic Le Marchand, David Van Den Berg, Brian E Henderson, Daniel O Stram
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2013-03-01
Serija:PLoS Genetics
Online pristup:http://europepmc.org/articles/PMC3610631?pdf=render

Internet

http://europepmc.org/articles/PMC3610631?pdf=render

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