Possible frequent multiple mitochondrial DNA copies in a single nucleoid in HeLa cells

Abstract Previously, a number of ~ 1.4 of mitochondrial DNA (mtDNA) molecules in a single nucleoid was reported, which would reflect a minimum nucleoid division. We applied 3D-double-color direct stochastic optical reconstruction microscopy (dSTORM), i.e. nanoscopy with ~ 25–40 nm x,y-resolution, to...

Full description

Bibliographic Details
Main Authors: Vojtěch Pavluch, Tomáš Špaček, Hana Engstová, Andrea Dlasková, Petr Ježek
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33012-6