Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

The proteolysis targeting chimeras (PROTACs) technology has been rapidly developed since its birth in 2001, attracting rapidly growing attention of scientific institutes and pharmaceutical companies. At present, a variety of small molecule PROTACs have entered the clinical trial. However, as small m...

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Bibliographic Details
Main Authors: Sinan Ma, Jianai Ji, Yuanyuan Tong, Yuxuan Zhu, Junwei Dou, Xian Zhang, Shicheng Xu, Tianbao Zhu, Xiaoli Xu, Qidong You, Zhengyu Jiang
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Non-small molecule PROTACs
Protein degradation
Peptide PROTACs
Nucleic acid PROTACs
Antibody PROTACs
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522000788

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http://www.sciencedirect.com/science/article/pii/S2211383522000788

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